关节镜微创技术治疗中老年轻、中度膝关节骨性关节炎的效果及对其生活质量的影响

发布时间:2018-06-23 来源: 散文精选 点击:


  【摘要】 目的:探究关节镜微创技术治疗中老年轻、中度膝关节骨性关节炎的效果及对其生活质量的影响。方法:选择本院2016年4月1日-2018年1月1日收治的膝关节骨性关节炎患者70例,使用随机数字表法将所有患者分为对照组(30例)与观察组(40例)。对照组患者采用常规内科治疗,观察组在此基础上进行关节镜微创术治疗。分别测定两组患者血清超氧化物歧化酶(SOD)、超敏C反应蛋白(hs-CRP)、一氧化氮(NO)、肿瘤坏死因子α(TNF-α)水平,并对患者关节的疼痛肿胀、功能状况以及屈伸度进行评估,判定患者疗效。结果:观察组患者血清SOD水平显著高于对照组,hs-CRP、NO、TNF-α水平显著低于对照组(P<0.05)。观察组关节静息痛、压痛、肿胀指数显著低于对照组(P<0.05)。同时观察组关节功能评分及主动屈伸度显著高于对照组(P<0.05)。结论:关节镜微创术治疗膝关节骨性关节炎疗效显著,降低关节炎症水平,改善关节功能,值得临床推广。
  【关键词】 关节镜微创技术; 膝关节; 骨性关节炎
  The Effect of Minimally Invasive Arthroscopy in the Treatment of Mild and Moderate Knee Osteoarthritis in the Middle and Old Age and Its Effect on the Quality of Life/YE Heng,SU Peiqun,CHEN Youxuan.//Medical Innovation of China,2018,15(07):013-016
  【Abstract】 Objective:To explore the effect of minimally invasive arthroscopy in the treatment of mild and moderate knee osteoarthritis in the middle and old age and its effect on the quality of life.Method:70 patients with knee osteoarthritis were treated in our hospital from April 1,2016 to January 1,2018,according the random number table method,they were divided into control group(30 case) and observation group(40 case).The control group was treated with routine medical treatment,on the basis of the observation group was given minimally invasive arthroscopic treatment.The serum superoxide dismutase(SOD),high sensitive C reactive protein (hs-CRP),nitric oxide (NO),tumor necrosis factor α (TNF-α) level,patients with joint pain and swelling,flexion and extension function evaluation,the curative effect of two groups were compared.Result:The level of serum SOD in observation group was significantly higher than that of the control group,hs-CRP, NO, TNF-αlevels were significantly lower than those of the control group(P<0.05).The observation group of joint rest pain,tenderness,swelling index were significantly lower than those of the control group(P<0.05).At the same time,the joint function score and active flexion in observation group were significantly higher than those of the control group(P<0.05).Conclusion:Arthroscopic minimally invasive surgery has significant therapeutic effect on osteoarthritis of the knee joint,reduces inflammation,improves joint function,it is worthy of promotion.
  【Key words】 Arthroscopy minimally invasive technique; Knee joint; Osteoarthritis
  First-author’s address:The People’s Hospital of Chaozhou,Chaozhou 521000,China
  doi:10.3969/j.issn.1674-4985.2018.07.004
  膝关节骨性关节炎(knee osteoarthritis,KOA)是一种多因素引起的疾病,多发于中年老人群,因此又被称为老年性关节炎[1]。临床研究显示,高龄、肥胖、创伤及关节先天性疾病等因素均可导致OA发生,OA患者存在关节软骨退化、关节及软骨反应性增生,主要临床表现为关节疼痛、僵硬及功能障碍等[2-3]。其症状多在清晨起床时出现,在大量体力劳动后可明显加重,因此患者多因出现关节严重疼痛而就诊。体格检查可发现病变关节明显肿胀、压痛,活动屈伸时存在明显摩擦感或出现咔嗒声等现象,严重情况可有关节畸形、肌肉萎缩等严重症状,X线检查可观察到关节四周骨赘明显增生变形、间隙狭窄等表现[4]。由于OA患者可出现严重的疼痛感及关节活动度受限,因此其生活质量明显降低。目前治疗骨关节炎的治疗方法较多,其目的主要是用于缓解关节疼痛、提高患者的关节活动度,同时使患者受损软骨及正常骨结构得到重建恢复,进而缓解病情[4]。随着关节镜技术的普及,目前关节镜微创术在治疗膝骨关节炎方面具有很大優势。本文通过对观察组采用关节镜微创术,评估其临床效果,现报道如下。

相关热词搜索:膝关节 对其 关节炎 中老年 生活质量

版权所有 蒲公英文摘 www.zhaoqt.net